Symbol
Name
ID

Ccr6
C-C motif chemokine receptor 6
MGI:1333797

Phenotype annotations related to immune system

Darker colors indicate more annotations

Mouse Phenotypes

increased T cell proliferation

increased double-positive T cell number

increased B-1 B cell number

decreased B cell number

decreased CD4-positive, alpha-beta T cell number

decreased CD8-positive, alpha-beta T cell number

abnormal intraepithelial T cell number

increased T cell number

increased activated T cell number

decreased leukocyte cell number

increased leukocyte cell number

abnormal myeloid dendritic cell morphology

abnormal lymphocyte morphology

abnormal CD4-positive, alpha beta T cell morphology

abnormal CD4-positive, alpha-beta intraepithelial T cell morphology

abnormal CD8 positive, alpha-beta intraepithelial T cell morphology

abnormal alpha-beta intraepithelial T cell morphology

abnormal effector T cell morphology

abnormal peritoneal macrophage morphology

abnormal spleen morphology

impaired eosinophil recruitment

abnormal B cell physiology

decreased IgA level

decreased IgE level

decreased IgG3 level

increased IgM level

abnormal T cell physiology

abnormal CD4-positive, alpha-beta T cell physiology

abnormal macrophage physiology

decreased macrophage cytokine production

decreased macrophage nitric oxide production

abnormal gut-associated lymphoid tissue morphology

abnormal Peyer's patch morphology

abnormal Peyer's patch follicle morphology

abnormal Peyer's patch T cell area morphology

abnormal Peyer's patch germinal center morphology

decreased Peyer's patch number

abnormal dendritic cell physiology

decreased susceptibility to type I hypersensitivity reaction

abnormal follicular dendritic cell antigen presentation

abnormal follicular dendritic cell physiology

increased interferon-gamma secretion

abnormal interleukin secretion

decreased interleukin-10 secretion

decreased interleukin-12 secretion

decreased interleukin-4 secretion

decreased interleukin-5 secretion

decreased tumor necrosis factor secretion

decreased susceptibility to experimental autoimmune encephalomyelitis

decreased inflammatory response

decreased susceptibility to bacterial infection

increased susceptibility to Riboviria infection

Availability

Mouse Genotype

Ccr6^tm1(EGFP)Irw/Ccr6^tm1(EGFP)Irw

Ccr6^{tm1.1(KOMP)Vlcg}/Ccr6^{tm1.1(KOMP)Vlcg}

Ccr6^tm1.1Jmf/Ccr6^tm1.1Jmf

Ccr6^tm1Gma/Ccr6^tm1Gma

Ccr6^tm1Gma/Ccr6^tm1Gma
Tg(Rorc-EGFP)1Ebe/?

Ccr6^tm1Lira/Ccr6^tm1Lira

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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